Spray Skid & Particle Formation by Supercritical Fluids

Principle

Multi-process laboratory skid: FAME (Fluid Assisted Micro-Encapsulation) and SAS (Supercritical AntiSolvent). This skid allows atomization thanks to the properties of supercritical CO2. It is mainly composed of :

– Two high pressure autoclaves
– A CO2 pump
– A co-solvent pump
– A compressor
– A chiller
– A hot bath
– A spillway

Principle and operation

SAS (Supercritical AntiSolvent) : It consists in solubilizing the material in an organic solvent, then contacting the solution thus formed with a supercritical fluid (CO2 in general). This phenomenon will lead to the precipitation or recrystallization of the material, which will then be in the form of a fine powder. The supercritical fluid appears as an anti-solvent. This process is called SAS, for Supercritical Anti-Solvent.

FAME (Fluid Assisted Micro Encapsulation) : It consists in solubilizing supercritical CO2 in a material until saturation. This mixture is then depressurized and expanded.

CUSTOMER INFORMATION

Product concerned

Multiproducts

Business sector 

Academic

Type of process

Atomization thanks to supercritical CO2: FAME and SAS

Constraints

Ergonomics
DESP

CHARACTERISTICS

Dimensions

Height 1.7 m Length 1.5 m Width 0.7 m

TANK VOLUME

One 300 mL preparation tank, One 1 L spray tank

IMPLEMENTATION DEADLINE

6 months

PRESSURE & FLOW RATE

Operating conditions max. 400 bar / 300 °C